Disorders & Diseases

-

 Thalassaemia is an inherited blood disorder. It happens when a child receives faulty haemoglobin genes from one or both parents.

Step-by-step:

  1. Haemoglobin is the protein inside red blood cells that carries oxygen.
  2. Haemoglobin is made of protein chains called alpha chains and beta chains.
  3. The instructions for making these chains are stored in genes.
  4. If there is a mutation (change) in these genes, the body cannot make enough normal haemoglobin.
  5. As a result, red blood cells become weak, small, and are destroyed more quickly than normal.
  6. This leads to anaemia (low number of healthy red blood cells).

How is it inherited?

If both parents are carriers of thalassaemia trait:

  • 25% chance the child will have normal genes.
  • 50% chance the child will be a carrier (thalassaemia minor).
  • 25% chance the child will have thalassaemia major (severe disease).

Comments

Post a Comment

Popular posts from this blog

Chemistry Final Exams Question Bank and answers

-
Chemistry Revision: Set 1 1. Define Oxidation Number and Reduction Oxidation Number: It is the formal charge that an atom appears to have in a chemical species when all shared electrons are counted as belonging to the more electronegative atom. It is a theoretical tool used to track electron flow. Reduction: In terms of electron transfer, reduction is the gain of electrons by an atom or ion. In terms of oxidation number, it is the decrease in the oxidation state of an element. Reaction: Cu 2+ + 2e - → Cu Example: Copper is reduced as its oxidation number changes from +2 to 0. 2. State and Explain Mendeleev’s Periodic Law Statement: The physical and chemical properties of elements are a periodic function of their atomic masses . Arrangement: Mendeleev arranged the then-known 63 elements in increasing order of at...
Read more

solid state 12th cet mht

-
Solid State MCQ Practice Chemistry | MHT-CET Previous year questions with detailed solutions MHT-CET 2015 Q1. Select a ferromagnetic material from the following. (A) Dioxygen (B) Chromium(IV) oxide (C) Benzene (D) Dihydrogen monoxide Correct Answer (B) Chromium(IV) oxide Detailed Explanation: Ferromagnetism: These are substances that show permanent magnetism even when an external magnetic field is removed. This happens because the magnetic moments (domains) align spontaneously in the same direction. While common metals like Iron (Fe), Cobalt (Co), and Nickel (Ni) are ferromagnetic, Chromium(IV) oxide (CrO 2 ) is a key example of a ferromagnetic metallic oxide. Due to ...
Read more